Capital Optimal
- Details
- Category: p1
- Published on 11 March 2013
- Hits: 10309
The Next Step Forward in Silica Engineering
The Next Step Forward in Silica Engineering The new range of Optimal® HPLC columns from Capital HPLC respresents the next step forward in porous silica engineering beyond the so-called new generation high purity materials. |
![]() |
Specifications
The fact that high purity Optimal is manufactured using well established silica engineering techniques means that a wide range of specifications are possible. As a result, we can supply Optimal in pore sizes ranging from 60Å to 1000Å with the most popular being 120Å. Moreover, Optimal is also available in particle sizes ranging from 3μm up to preparative grade sizes. |
Shape: Phases Available: Particle Size: Mean Pore Diameter: Carbon Loading: Specific Surface Area: |
Spherical ODS-H, ODS-L, C8 and Silica 3μm, 5μm and larger 120Å (300, 500 and 1000Å also available) ODS-H (18%), ODS-L (15%) 320m2g-1. (120Å material) |
Optimal® ODS-H
Optimal® ODS-H is the most generally applicable of the Optimal® phases and can be used for both specialist
applications involving acid and basic compounds or mixtures of both. Optimal® ODS-H is also particularly well
suited to general purpose method development.
![]() |
The absence of active silanols in Optimal is illustrated by this Column: Optimal® ODS-H 5μm |
![]() |
Neutral silanol groups can still occasionally cause problems Column: Optimal® ODS-H 5μm 1. Theobromine, 2. Theophylline
|
Many compounds such as polyphenols interact irreversibly with the active sites on silica based reversed
phase materials. In the case of Optimal ODS-H this problem does not occur, which makes it possible
to analyse problematic compounds such as in the example below.
![]() |
Column: Optimal® ODS-H 5μm Dimensions: 15cm x 4.6mm Mobile Phase: 25:75 Methanol:Water Temperature: 30°C Flow Rate: 1ml/min Detection: UV at 254nm
![]()
|
Silianol Sensitive Vitamins Column: Optimal® ODS-H 5μm Temperature: 40°C 1. Thiamine Hydrochloride |
![]()
|
Tricyclic Antidepressives Column: Optimal® ODS-H 5μm Temperature: 40°C 1. Protriptyline
|
![]()
|
Optimal® ODS-L
Optimal® ODS-L has a slightly lower carbon loading (15%) than the ODS-H and is useful for the analysis of a wide range of hydrophilic compounds which are normally not retained by other C18 based packing material. Optimal ODS-L is also as useful for analysing hydrophobic samples which are currently chromatographed on competitor C8 materials. Like ODS-H, this packing material is also fully endcapped. OptimalODS-L is also based on the same high purity silica as the Optimal ODS-H material which ensures the high degree of inertness and lack of peak tailing. |
Fructo-Oligosaccharides Column: Optimal® ODS-H 5μm
1. Sucrose
|
![]()
|
Optimal Ordering Information
Catalogue numbers refer to 5μm materials 4.6mm column i.d. only. For 2.1mm or 3.2mm
diameter columns please add D2 and D3 respectively to the standard 4.6mm i.d. columns.
Prices for 2.1mm and 3.2mm i.d. columns are as for 4.6mm i.d.
New Precision Format Columns
5mm prices only (3μm and 10μm particles are also available)
Phase 2cm 5cm 10cm 15cm 20cm 25cm |
(guard) |
Silica 5SA102 5SA105 5SA110 5SA115 5SA120 5SA125 |
C8 5SF102 5SF105 5SF110 5SF115 5SF120 5SF125 |
ODS-H 5SG102 5SG105 5SG110 5SG115 5SG120 5SG125 |
ODS-L 5SH102 5SH105 5SH110 5SH115 5SH120 5SH125 |
PRICE/£ See price list page 1 |
UCCCartridgeFormatColumns
5µm prices only (3µmand 10µmparticles are also available)
Phase 2cm 5cm 10cm 15cm 20cm 25cm |
(guard) |
Silica 5SA102 5SA305 5SA310 5SA315 5SA320 5SA325 |
C8 5SF102 5SF305 5SF310 5SF315 5SF320 5SF325 |
ODS-H 5SG102 5SG305 5SG310 5SG315 5SG320 5SG325 |
ODS-L 5SH102 5SH305 5SH310 5SH315 5SH320 5SH325 |
PRICE/£ See price list page 1
|
Wide Pore Materials
All Capital HPLC Optimal columns are available in various pore sizes ranging from 60Å up to
1000Å. This makes it possible to analyse larger molecules together with all the advantages of
a high purity, highly inert material. For prices and ordering information for wide pore materials,
please consult our price list, page 1.